This is something I have done – partaken of – in bits and bobs since 2004. With the move to the WordPress.com servers, Domain mapping to the same and a move from Gmail to Google Apps – BTW looks and acts the same – I seem to be right in the middle of it.
The trick is a work flow that suits each step and learning to admit defeat, quickly, when the next bright shiny idea/widget doesn’t gel. Give and take is the saying.
Cloud computing a Wikipedia explanation. And Stephen Fry, yes that Stephen Fry, weighs in. I don’t understand the terms and conditions on Stephen’s blog so here we have a cut and paste instead of the usual live link.